Life Science Research

LIFE SCIENCE RESEARCH

Comino designs and manufactures powerful multi-GPU workstations for enabling rapid large-scale data processing, complex molecular simulations, and AI model training that deliver 3-30× speedups for genomics workflows, virtual screening of billions of compounds, and AlphaFold-level protein structure prediction.

Optimized for specialized Life Science software

Cryo-EM & Structural Biology

CryoSPARC, Relion

Molecular Dynamics & Drug Discovery

GROMACS, AMBER, NAMD, CHARMM, OpenMM

Genomics & Sequencing

GATK, BWA, SAMtools, BEDtools, Picard, STAR, HISAT2

Medical Imaging & Analysis

ITK, VTK, DICOM, 3D Slicer, ImageJ, FSL, FreeSurfer

Computational Biomechanics

Ansys

Key benefits for Life Science research

Complete data privacy & security

on-premise deployment ensures sensitive medical and genomic data never leaves your secure environment, critical for HIPAA/GDPR/FDA compliance and proprietary research data protection

Sustained high performance

up to 50% higher performance, 100% of time at Boost Clocks, zero thermal throttling, eliminates performance degradation during long-running simulations that can span days or weeks

Long-term reliability

up to 3 years of maintenance-free operation, stable thermal management prevents system failures during critical research workflows where interruptions can cost millions of dollars

Fast storage & high-bandwidth networking

optimized for CryoSPARC shared file system, Relion fast storage requirements, Ansys NVMe SSD specifications, supports 10Gbps network requirements

Ultra-low noise operation

minimal noise even at full load, ideal for quiet laboratory environments where researchers work alongside systems

TECHNOLOGY

Liquid cooling technology

engineered for sustained performance: low flow rate 1-1.5 liters/min (vs 3-5 liters in competitors), low system pressure reduces leak risk, operates 100% of time at Boost Clocks, eliminates thermal throttling entirely, up to 50% higher sustained performance compared to air-cooled alternatives

Engineered, not assembled approach

custom-designed water blocks fit in single PCIe slot (most competitors take two slots), cools power delivery circuits (motherboard VRM) — unique feature, works with hot air up to 35-40°C (no need for air conditioning), enables deployment in existing laboratory infrastructure without HVAC upgrades

On-premise deployment architecture

complete data privacy through secure on-premise infrastructure, critical for HIPAA/GDPR/FDA compliance and proprietary research data

Energy-efficient design

cooling system consumes 300W (vs 2000W air-cooled), low operating temperatures 60-65°C for CPU (vs 90-95°C in laptops, 80+°C for GPU in air-cooled), up to 40% overall energy savings

CONFIGURATIONS

GRANDO Life Science Research Workstation for Cryo-EM & Structural Biology (CryoSPARC, Relion)

CryoSPARC Master Node

CPU: Threadripper PRO 7975WX (32 cores)

RAM: 32GB DDR4

DRIVES: 500GB SSD

(8+ cores at 2.8GHz+ recommended)

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CryoSPARC Worker Node

GPUS: NVIDIA L40S x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 256GB DDR4

(64GB per GPU recommended)

DRIVES: 2x 2TB NVMe PCIe SSD

(4 cores per GPU, CPU memory bandwidth 100+ GB/s recommended)

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Relion Multi-GPU

GPUS: NVIDIA RTX 5090 x 2

CPU: Threadripper PRO 7975WX (32 cores)

RAM: 256GB

DRIVES: 2x 2TB NVMe PCIe SSD

(optimized for Refine3D odd MPI configuration)

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Relion High-Performance

GPUS: NVIDIA H200 x 4

CPU: Threadripper PRO 7995WX (96 cores)

RAM: 1024GB

DRIVES: 2x 2TB NVMe PCIe SSD

(supports Class2D, Class3D, MultiBody, CPU-only jobs)

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GRANDO Life Science Research Workstation for Genomics & Bioinformatics

Workstation

GPUS: NVIDIA RTX 5090 x 2

CPU: Threadripper PRO 7975WX (32 cores)

RAM: 256GB

DRIVES: 2x 2TB NVMe

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Workstation

GPUS: NVIDIA L40S x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 512GB

DRIVES: 2x 3.84TB NVMe

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Workstation

GPUS: AMD Radeon AI PRO R9700 x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 512GB

DRIVES: 2x 3.84TB NVMe

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GRANDO Life Science Research Workstation for Computational Biomechanics (Ansys)

Ansys Structural FEA (Sparse Direct Solver)

GPUS: NVIDIA RTX 5090 x 2

CPU: Threadripper PRO 7975WX (32 cores)

RAM:96GB+ DDR4

(minimum 48 GB for in-core solution)

DRIVES: 2x 2TB NVMe SSD

(high-frequency CPUs 3.4+ GHz, 2666+ MHz memory, 45 GB per million solid nodes)

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Ansys CFD / Structural FEA (PCG Iterative Solver)

GPUS: NVIDIA L40S x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 512GB

DRIVES: 2x 2TB NVMe SSD

(GPU-accelerated PCG iterative solver, multiple GPUs with sufficient VRAM, requires HPC Pack license, high memory bandwidth for CFD)

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Ansys NVH

GPUS: NVIDIA RTX 5090 x 2

CPU: Threadripper PRO 7975WX (32 cores)

RAM: 256GB+ DDR4

(high memory capacity)

DRIVES: 2x 2TB NVMe SSD

(intermediate endurance ~0.3 DWPD, not QLC NAND)

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GRANDO Life Science Research Workstation for Molecular Dynamics & Drug Discovery

Workstation

GPUS: NVIDIA L40S x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 512GB

DRIVES: 2x 7.68TB NVMe

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Workstation

GPUS: NVIDIA H200 x 4

CPU: Threadripper PRO 7995WX (96 cores)

RAM: 1024GB

DRIVES: 2x 7.68TB NVMe

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GRANDO Life Science Research Workstation for Medical Imaging Analysis

Workstation

GPUS: NVIDIA RTX 5090 x 2

CPU: Threadripper PRO 7975WX (32 cores)

RAM: 256GB

DRIVES: 2x 2TB NVMe

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Workstation

GPUS: NVIDIA L40S x 4

CPU: Threadripper PRO 7985WX (64 cores)

RAM: 512GB

DRIVES: 2x 3.84TB NVMe

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COMINO GRANDO FOR LIFE SCIENCE RESEARCH